Frozen vaccines should be stored below which temperature?

Vaccines that require frozen storage are typically kept at temperatures below 0 degrees Fahrenheit. This ensures their efficacy and stability, as vaccines can degrade if not stored at the recommended temperatures. Most guidelines specify that frozen vaccines should be stored at -58 degrees F to the manufacturer's recommended temperature, which is often around -20 degrees Celsius, translating roughly to 0 degrees Fahrenheit.

While storing vaccines in the -5 to -10 degrees F range may slow down degradation, it does not guarantee the same level of efficacy as storage at the required temperature. Therefore, the correct answer aligns with the standard practice of keeping frozen vaccines at or below 0 degrees Fahrenheit to maintain their potency and effectiveness over time.